SCHEDULE |
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| DATE | OPPONENT | CLASS | LOCATION | VAR TIME | RESULT | SCORE | PTS |
| 12/1/2021 |
at Lewiston-Porter
|
B | Lewiston-Porter HS | 7:00 PM | L | 32-50 | - |
| 12/3/2021 |
International Prep
|
A | Lake Shore HS | 6:30 PM | L | 48-71 | - |
| 12/7/2021 |
at Cheektowaga
|
A | Cheektowaga HS | 6:30 PM | L | 43-55 | 0.0 |
| 12/10/2021 |
at Iroquois
|
A | Iroquois HS | TBA | L | 58-72 | - |
| 12/13/2021 |
West Seneca East
|
A | Lake Shore HS | 6:30 PM | W | 50-47 | - |
| 12/16/2021 |
Lackawanna
|
B | Lake Shore HS | 5:30 PM | L | 52-82 | - |
| 12/18/2021 |
Hamburg
|
A | Frontier HS | 1:30 PM | L | 32-60 | - |
| 12/21/2021 |
at East Aurora
|
B | East Aurora HS | 7:00 PM | W | 53-50 | 5.0 |
| 1/11/2022 |
at Maryvale
|
B | Maryvale HS | 6:30 PM | L | 40-63 | 0.0 |
| 1/13/2022 |
at Pioneer
|
A | Pioneer HS | 7:00 PM | L | 26-57 | 0.0 |
| 1/15/2022 |
Springville-Griffith
|
B | Lake Shore HS | 11:30 AM | W | 47-32 | 5.0 |
| 1/18/2022 |
East Aurora
|
B | Lake Shore HS | 6:30 PM | L | 48-56 | 0.0 |
| 1/25/2022 |
Cheektowaga
|
A | Lake Shore HS | 6:30 PM | W | 62-54 | 6.0 |
| 1/27/2022 |
Depew
|
B | Lake Shore HS | 6:30 PM | L | 42-44 | 0.0 |
| 2/1/2022 |
Maryvale
|
B | Lake Shore HS | 6:30 PM | L | 45-63 | 0.0 |
| 2/5/2022 |
at Depew
|
B | Depew HS | 1:00 PM | L | 29-62 | 0.0 |
| 2/7/2022 |
Pioneer
|
A | Lake Shore HS | 6:30 PM | L | 41-69 | 0.0 |
| 2/8/2022 |
at Springville-Griffith
|
B | Springville-Griffith HS | 6:30 PM | W | 55-48 | 5.0 |
| 2/10/2022 |
Cardinal O'Hara
|
B | Lake Shore HS | 6:30 PM | L | 63-64 | - |
| 2/16/2022 |
Buffalo Science
|
C | Lake Shore HS | 6:30 PM | W | 64-36 | - |
| 2/22/2022 |
at Albion
|
B | Albion HS | 7:00 PM | L | 50-53 | - |